pmorales@med.uchile.cl

Doctorado en Ciencias Biomédicas PhD. 2005

Magister en Ciencias mención Neurobiología y Cs de la Conducta

Facultad de Medicina, ICBM, Universidad de Chile.

Líneas de investigación

Mecanismos de reparación neuronal, plasticidad cerebral, neurogénesis postnatal

Publicaciones Recientes

Marriott AL, Rojas-Mancilla E, Morales P, Mario Herrera- Marschitz,       Tasker RA. 2015. “Models of progressive neurological dysfunction originating early in life Progress” in Neurobiol. In press ISSN: 0301-0082, IF: 9.992

Herrera-Marschitz M, Neira-Peña T, Rojas-Mancilla E, Morales P, Bustamante D, Leyton L, Gebicke-Haerter P. 2015. “Short- and long-term consequences of perinatal asphyxia: looking for neuroprotective strategies”. Adv Neurobiol. 2015; 10: 169-98. doi: 10.1007/978-1-4939-1372-5_9.PMID: 25287541 [PubMed – in process] ISSN: 2190-5215, IF:.1.05

Neira-Peña T, Rojas-Mancilla E, Munoz-Vio V, Perez R, Gutierrez-Hernandez M, Bustamante D, Morales P, Hermoso MA, Gebicke-Haerter P, Herrera-Marschitz M. Perinatal 2015. “Asphyxia Leads to PARP-1 Overactivity, p65 Translocation, IL-1β and TNF-α Overexpression, and Apoptotic-Like Cell Death in Mesencephalon of Neonatal Rats: Prevention by Systemic Neonatal Nicotinamide Administration”. Neurotox Res. 2015 May;27(4):453-65. doi: 10.1007/s12640-015-9517-0. Epub 2015 Feb 10. PubMed PMID: 25835215; PubMed Central PMCID: PMC4383817. ISSN: 1029-8428 IF: 3.54

Quintanilla ME, Rivera-Meza M, Berrios-Cárcamo PA, Bustamante D, Buscaglia M, Morales P, Karahanian E, Herrera-Marschitz M, Israel Y. 2014. « Salsolinol, free of isosalsolinol, exerts ethanol-like motivational/sensitization effects leading to increases in ethanol intake”. Alcohol. 2014 Sep;48(6):551-9. doi: 10.1016/j.alcohol.2014.07.003. Epub 2014 Jul 14. PMID: 25086835.       ISSN 0741-8329, IF: 5.93

Israel Y, Rivera-Meza M, Karahanian E, Quintanilla ME, Tampier L, Morales P, Herrera- Marschitz M (2013) “Gene specific modifications unravel ethanol and acetaldehyde actions”. Front Behav Neurosci. 2013 Jul 8;7:80. doi: 0.3389/fnbeh.2013.00080. PMID: 23847486, ISSN: 1662-5153, IF: 3.3

Allende-Castro C, Espina-Marchant P, Bustamante D, Rojas-Mancilla E, Neira T, Gutierrez-Hernandez MA, Esmar D, Valdes JL, Morales P, Gebicke-Haerter PJ, Herrera-Marschitz M (2012). “Further Studies on the Hypothesis of PARP-1 Inhibition as a Strategy for Lessening the Long-Term Effects Produced by Perinatal Asphyxia: Effects of Nicotinamide and Theophylline on PARP-1 Activity in Brain and Peripheral Tissue : Nicotinamide and Theophylline on PARP-1 Activity”. Neurotox Res. Jul;22(1):79-90. Epub 2012 Feb 4. ISSN: 1029-8428. IF: 3.54

Herrera-Marschitz M, Morales P, Leyton L, Bustamante D, Klawitter V, Espina-Marchant P,Allende C, Lisboa F, Cunich G, Jara-Cavieres A, Neira T, Gutierrez M, Gonzalez-Lira V, Simola N,Schmitt A, Morelli M, Tasker RA, Gebicke-Haerter PJ. (2011) “Perinatal asphyxia: current status and approaches towards neuroprotective strategies, with focus on sentinel proteins”. Neurotoxicity Research, 19:603-627. Publicada. ISSN: 1029-8428 IF: 3.54

Morales P, Bustamante D, Espina-Marchant P, Neira-Peña T, Gutiérrez-Hernández MA, Allende-Castro C and Rojas-Mancilla E. 2011. « Pathophysiology of perinatal asphyxia: can we predict and improve individual outcomes? » EPMA Journal (2011) 2:211–230 DOI 10.1007/s13167-011-0100-3 ISSN: 1878-5085.

Karahanian E, Quintanilla ME, Tampier L, Rivera-Meza M, Bustamante D,Gonzalez-Lira V, Morales P, Herrera-Marschitz M, Israel Y. 2011. “Ethanol as a Prodrug: Brain Metabolism of Ethanol Mediates its Reinforcing Effects ». Alcohol Clin Exp Res. 2011 Apr;35(4):606-612. doi: 10.1111/j.1530-0277.2011.01439.x. Epub 2011 Feb17. PubMed PMID: 21332529. ISSN: 1530-0277, IF: 3.205

Ulloa JL, Castañeda P, Berríos C, Díaz-Veliz G, Mora S, Bravo JA, Araneda K,Menares C, Morales P, Fiedler JL. 2010. “Comparison of the antidepressant sertraline on differential depression-like behaviors elicited by restraint stress and repeated corticosterone administration ». Pharmacol Biochem Behav. 2010 Dec;97(2):213-21. Epub 2010 Aug 10. PubMed PMID: 20705085. ISSN: 0091-3057, IF: 2.781