melopez@med.uchile.cl

Doctor en Ciencias Biomédicas

Universidad de Chile, 2009

Chile

Líneas de Investigación

Inmunología del Cáncer.

Inmunoterapia Oncológica.

Publicaciones Recientes

Pérez CA, Rabanales R, Rojas-Alcayaga G, Larrondo M, Escobar AF, López MN, Salazar-Onfray F, Alfaro JI, González FE. 2015 “Dendritic cell chimerism in oral mucosa of transplanted patients affected by graft-versus-host disease”. J Oral Pathol Med. Jun 23. doi: 10.1111/jop.12338. ISSN: 1600-0714. IF: 1.926.

 

González FE, Gleisner A, Falcón-Beas F, Osorio F, López MN, Salazar-Onfray F. 2014 “Tumor cell lysates as immunogenic sources for cancer vaccine design”. Hum Vaccin Immunother. 10 (11):3261-9. ISSN: 2164-554X. IF: 2.366.

 

Tapia CV, Falconer M, Tempio F, Falcón F, López MN, Fuentes M, Alburquenque C, Amaro J, Bucarey SA, Di Nardo A. 2014 “Melanocytes and melanin represent a first line of innate immunity against Candida albicans”. Med Mycol. Jul 1;52(5):445-54. ISSN: 1369-3786. IF:2.26.

 

González FE, Ortiz C, Reyes M, Dutzan N, Patel V, Pereda C, Gleisner MA, López MN, Gutkind JS, Salazar-Onfray F. 2014. “Melanoma cell lysate induces CCR7 expression and in vivo migration to draining lymphnodes of therapeutic human dendritic cells”. Immunology. Jul;142(3):396-405. ISSN: 1365-2567. IF: 3.795.

 

Tittarelli A, Mendoza-Naranjo A, Farías M, Guerrero I, Ihara F, Wennerberg E, Riquelme S, Gleisner A, Kalergis A, Lundqvist A, López MN, Chambers BJ, Salazar-Onfray F. 2014. “Gap junction intercelular communications regulate NK cell activation and modulate NK cytotoxic capacity”. J Immunol. 2014;192(3):1313-9. ISSN: 1550-6606. IF: 5.362.

 

Escobar A, Aguirre A, Guzmán MA, González R, Catalán| D, Acuña-Castillo C, Larrondo M, López MN, Pesce B, Rolland J, O`Hehir R, Aguillón JC. 2014 “Tolerogenic dendritic cells derived from donors with natural rubber latex allergy modulate allergen-specific T-cell responses and IgE production”. PLoSOne. 2014 Jan 22;9(1):e85930. ISSN: 1932-6203. IF: 3.534.

 

 

Salazar-Onfray F, Pereda C, Reyes D, López MN. 2013. “TAP Cells, the Chilean dendritic cell vaccine against melanoma and prostate cancer”. Biol Res.;46(4):431-40. ISSN: 0717-6287. IF: 1.480.

 

Escobar A, Candia E, Reyes-Cerpa S, Villegas-Valdes B, Neira T, Lopez MN, Maisey K, Tempio F, Ríos M, Acuña-Castillo C, Imarai M. 2013. “Neisseria gonorrhoeae induces a tolerogenic phenotype in macrophages to modulate host immunity”. Mediators Inflamm.; 2013:127017. ISSN: 1466-1861. IF: 2.417.

 

 

Reyes D, Salazar L, Espinoza E, Pereda C, Castellón E, Valdevenito R, Huidobro C, Becker MI, Lladser A, López MN, and Salazar-Onfray F. 2013 “Tumor cell lysate loaded-dendritic cell vaccine induces biochemical and memory immune response in castration-resistant prostate cancer patients”. Br Journal of Cancer. Br J Cancer. 109(6):1488-97. ISSN: 0007-0920. IF:4.817 (2013-2014)

 

Durán-Aniotz C, Segal G, Salazar L, Pereda C, Falcón C, Tempio F, Aguilera R, González R, Pérez C, Tittarelli A, Catalán D, Nervi B, Larrondo M, Salazar-Onfray F, López MN. 2013. “The immunological response and post-treatment survival of DC-vaccinated melanoma patients are associated with increased Th1/Th17 and reduced Th3 cytokine responses”. Cancer Immuno lImmunother; 62(4):761-72. ISSN: 1432-0851. IF: 3.943