• Licenciado en Medicina 1976, Universidad de Chile, Chile
  • Médico Cirujano 1978, Universidad de Chile, Chile
  • Pediatra 1986, Universidad de Chile, Chile
  • Posdoctoral Fellow, Infectious Diseases (1989-1994). St. Jude Children’s Research Hospital, Memphis, TN, EEUU
  • Infectólogo, CONACEM, 1994, Chile

Líneas de Investigación

  • Epidemiología molecular e Interacción patógeno-hospedero en el patógeno pulmonar Pneumocystis.
  • Estudios clínicos de fase 2 y 3 para evaluación de fármacos en medicina e infectología respiratoria.

Publicaciones Recientes

1.- Pérez FJ, Ponce CA, Rojas DA, Iturra PA, Bustamante RI, Gallo M, Hananias K, Vargas SL. 2014. Fungal colonization with Pneumocystis correlates to increasing chloride channel accessory 1 (hCLCA1) suggesting a pathway for up-regulation of airway mucus responses, in infant lungs”. Results Immunol. ISSN: 2211-2839.

2.- Ponce CA, Bustamante RI, Gallo M, Vargas SL.. 2014. “Diagnosis of the primary infection by pneumocystis in autopsy specimens from two infants using lung impression smears (touch preps)”. Med Mycol Case Rep. ISSN: 2211-7539. IF:

3.- Perez F, Mendez A, Lagos A, Vargas, SL. 2014. Mucociliary clearance system in lung defense”. Revista Medica de Chile. ISSN: 0034-9887. IF: 0.304

4.- Iturra, P, Perez, F, Ponce, CA, Vargas SL. 2014. Naturally acquired primary infection by pneumocystis induces airway epithelium and peri-vascular lung pathology in immunocompetent young rats”. PEDIATRIC PULMONOLOGY. ISSN: 1099- 0496. IF: 2.704

5.- Perez, F, Ponce, CA, Rojas, DA, Vargas SL. 2014. Relative contribution of viruses and ca2+-activated cl- channel 1 to Pneumocystis-associated increased expression of muc5ac in autopsied infant lungs”. PEDIATRIC PULMONOLOGY. ISSN: 1099- 0496. IF: 2.704

6.- Ortega HG, Liu MC, Pavord DM, Brusselle GG, et. al. Participant investigators: S. Vargas and others. 2014. “Mepolizumab tratment in patients with eosinophilic asthma”. New England Journal of Medicine. ISSN: 0028-4793. IF: 55.873

7.- Vargas SL, Ponce CA,Gallo M, Perez JF,. Durand-Joly I, Perez F, 2013. “Near-Universal Prevalence of Pneumocystis and Associated Increase in Mucus in the Lungs of Infants With Sudden Unexpected Death”. Clinical Infectious Diseases.. ISSN: 1537-6591. IF: 8.886

8.- Pavord ID, Kam S, Howarth P, Bleecker E, et. al. Participant Investigators: S Vargas and others. 2012. “Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial”. Lancet.. ISSN: 0140-6736. IF: 45.217

 9.- Vargas, SL , Pizarro, P , Lopez-Vieyra, M., Neyra P., Ponce CA. 2012.Pneumocystis Colonization in Older Adults and Diagnostic Yield of Single versus Paired Noninvasive Respiratory Sampling”. Clinical Infectious Diseases. ISSN: 1537-6591. IF: 8.886

10.- Ponce, CA , Gallo, M , Bustamante, R. Vargas, SL. 2010. Pneumocystis Colonization Is Highly Prevalent in the Autopsied Lungs of the General Population”. Clinical Infectious Diseases. ISSN: 1537-6591. IF: 8.886