kmarcelain@gmail.com

Doctora en Ciencias Biomédicas

Universidad de Chile, Chile, 2003

Líneas de Investigación

Inestabilidad genómica en cáncer

Publicaciones Recientes

Rivas S, Armisén R, Rojas DA, Maldonado E, Huerta H, Tapia JC, Espinoza J, Colombo A, Michea L, Hayman MJ, Marcelain K. 2015. “The Ski Protein is Involved in the Transformation Pathway of Aurora Kinase A”. J Cell Biochem. 2015 Jul 2. doi: 10.1002/jcb.25275. ISSN: 1097-4644. IF: 3.263

Colombo A, Palma K, Armijo L, Mione M, Signore IA, Morales C, Guerrero N, Meynard MM, Pérez R, Suazo J, Marcelain K, Briones L, Härtel S, Wilson SW, Concha ML. 2013. “Daam1a mediates asymmetric habenular morphogenesis by regulating dendritic and axonal outgrowth”. Development. 140 (19):3997-4007. ISSN: 1425-140X. IF 6.273

Meruane MA, Rojas M, Marcelain K. 2012. “The Use of Adipose Tissue-Derived Stem Cells within a Dermal Substitute Improves Skin Regeneration by Increasing Neoangiogenesis and Collagen Synthesis”. Plast Reconstr Surg. 2012 Jul; 130:53-63. ISSN: 0718-4026 IF: 3.238

Marcelain, K., Armisén, R., Aguirre, A., Ueki, N., Toro, J., Colmenares, C., and Hayman, M. J. 2012. “Chromosomal instability in mouse embryonic fibroblasts null for the transcriptional co-repressor Ski”. J Cell Physiol 227: 278-287. ISSN 1097-4652. IF: 3.874

Mosquera J, Armisen R, Zhao H, Rojas DA, Maldonado E, Tapia JC, Colombo A, Hayman MJ, Marcelain K. 2011 Identification of Ski as a target for Aurora A kinase. Biochem Biophys Res Commun. 409:539-43. ISSN 0006-291X. IF 2.281

Yefi, R., Ponce, D. P., Niechi, I., Silva, E., Cabello, P., Rodríguez, D. A., Marcelain, K., Armisén, R., Quest, A. F., and Tapia, J. C. 2011. “Protein kinaseCK2 promotes cancer cell viability via up-regulation of cyclooxygenase-2 expression and enhanced prostaglandin E2 production”. J Cell Biochem 112: 3167-3175. ISSN: 1097-4644. IF:3.368

Ponce, D. P., Yefi, R., Cabello, P., Maturana, J. L., Niechi, I., Silva, E., Galindo, M., Antonelli, M., Marcelain, K., Armisén, R., and Tapia, J. C. 2011. “CK2 functionally interacts with AKT/PKB to promote the beta-catenin-dependent expression of survivin and enhance cell survival”. Mol Cell Biochem 356: 127-132. ISSN: 0300-8177. IF 2.388

*Armisén R, *Marcelain K, *Simon F, Tapia JC, Toro J, Quest AF, Stutzin A. 2011. “TRPM4 enhances cell proliferation through up-regulation of the β-catenin signaling pathway. J Cell Physiol. 226:103-9. *Equal contributors. ISSN: 1097-4652. IF: 3.874

Zhao HL, Ueki N, Marcelain K, Hayman MJ. 2009. “The Ski protein can inhibitligand induced RARalpha and HDAC3 degradation in the retinoic acid signaling pathway”. Biochem Biophys Res Commun. 383:119-24. ISSN: 0006-291X. IF: 2.281

Pincheira J, Carrera P, Marcelain K, De La Torre C. 2008. “Hepatocytes, rather than leukocytes reverse DNA damage in vivo induced by whole body gamma-irradiation of mice, as shown by the alkaline comet assay”. Biol Res. ; 41:217-25. ISSN: 0717-6287. IF: 1.203