Doctor en Bioquímica. Universidad de Chile. 1990. Chile

Líneas de Investigación

Biología celular y molecular del cáncer

Publicaciones Recientes

  1. Cifuentes F, Valenzuela R, Contreras HR, Castellón EA. “Surgical cytorreduction of the primary tumor reduces metastatic progression in a mouse model of prostate cancer”. Oncol. Rep. (2015) (accepted, July 30, 2015). ISSN: 1021-335X. IF: 2.301.
  2. Cifuentes F, Valenzuela R, Contreras HR, Castellón EA. Development of an orthotopic model of human metastatic prostate cancer in the NOD-SCIDγ mouse (Mus musculus) anterior prostate. Oncol. Lett.. July, 22. (2015) (in press). ISSN: 1792-1074. IF: 1.554.
  3. Osorio L., Farfán N., Castellon EA., Contreras HR. “SNAIL transcriptional factor increased the motility and invasive capacity of prostate cancer cells”. Mol. Med. Rep. May, 21. (2015). (in press). ISSN: 1791-2997. IF: 1.554.
  4. Kato S, Abarzua-Catalan L, Trigo C, Delpiano A, Sanhueza C, García K, Ibañez C, Hormazábal K, Diaz D, Brañes J, Castellón E, Bravo E, Owen G, Cuello M. “Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women”. Oncotarget. May 22. [Epub ahead of print]. (2015). ISSN: 1949-2553. IF: 6.359
  5. Orellana R, Kato S, Erices R, Bravo ML, Gonzalez P, Oliva B, Cubillos S, Valdivia A, Ibañez C, Brañes J, Barriga MI, Bravo E, Alonso C, Bustamente E, Castellon E, Hidalgo P, Trigo C, Panes O, Pereira J, Mezzano D, Cuello MA, Owen GI. “Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells”. BMC Cancer. 15(1):290. (2015). ISSN: 1471-2407. IF: 3.362.
  6. jimenez de la Jara J, Bastias G, Ferreccio C, Moscoso C, Sagues S, Cid C, Bronstein E, Herrera C, Nervi B, Corvalan A, Velasquez EV, Gonzalez P, Castellon E, Bustamante E, Oñate S, McNerney E, Sullivan R, Owen GI. “A snapshot of cancer in Chile: analytical frameworks for developing a cancer policy”. Biol. Res. 48:10. (2015). doi: 10.1186/0717-6287-48-10. ISSN: 0716-9760. IF: 1.480.
  7. Orellana-Serradell O, Poblete CE, Sanchez C, Castellón EA, Gallegos I, Huidobro C, Llanos MN, Contreras HR. “Proapoptotic effect of endocannabinoids in prostate cancer cells”. Oncol Rep. 33(4):1599-608. (2015). doi: 10.3892/or.2015.3746. ISSN: 1021-335X. IF: 2.301.
  8. Castillo V, Valenzuela R, Huidobro C, Contreras HR, Castellon EA. “Functional characteristics of cancer stem cells and their role in drug resistance of prostate cancer”. Int J Oncol. 45(3):985-94. (2014). doi: 10.3892/ijo.2014.2529. ISSN: 1019-6439. IF: 3.025.
  9. Poblete CE, Fulla J, Gallardo M, Muñoz V, Castellón EA, Gallegos I, Contreras HR. “Increased SNAIL expression and low syndecan levels are associated with high Gleason grade in prostate cancer”. Int J Oncol. 44(3):647-54. (2014). doi: 10.3892/ijo.2014.2254. ISSN: 1019-6439. IF: 3.025.
  10. Marqués N., Sesé M., Cánovas V., Valente F., Bermudo R., de Torres I., Fernández Y., Abasolo I., Fernández P., Contreras H., Castellón E., Celià-Terrassa T., Méndez R., Ramón y Cajal S., Thomson T., Paciucci R. “Regulation of protein translation and c-Jun expression by Prostate Tumor Overexpressed 1. Oncogene”. 33(9):1124-34. (2014). doi: 10.1038/onc.2013.51. ISSN: 0950-9232. IF: 8.469.