Magister Ciencias Biológicas mención Fisiología. Facultad de medicina Universidad de Chile. 1988

Líneas de Investigación

Fisiología celular cardiovascular.

Regulación redox de proteínas


Publicaciones Recientes

Parra, VM, Macho, P, Sánchez, G, Donoso, P, Domenech, RJ. 2015. “Exercise preconditioning of myocardial infarct size in dogs is triggered by calcium”. J. Cardiovasc. Pharmacol. 65(3):276-81. ISSN: 1533-4023. IF: 2.111

Donoso P, Finkelstein, JP, Montecinos L, Said M, Sánchez G, Vittone L, Bull R. 2014 “Stimulation of NOX2 in isolated hearts reversibly sensitizes RYR2 channels to activation by cytoplasmic calcium”. J. Mol. Cel Cardiol; 68:38-46. ISSN: 0022-2828. IF: 4.655

Pedrozo Z, Torrealba N, Fernández C, Gatica D, Toro B, Quiroga C, Rodriguez AE, Sanchez G, Gillette TG, Hill JA, Donoso P, Lavandero S. 2013. “Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy”. Cardiovasc Res. 98:277-85. ISSN: 1755-3245. IF: 5.940

Sánchez G, Fernández C, Montecinos L, Domenech RJ, Donoso P. 2011. “Preconditioning tachycardia decreases the activity of the mitochondrial permeability transition pore in the dog heart”. Biochem Biophys Res Commun. 15; 410:916-21. ISSN: 0006-291X. IF: 2.297

 Hidalgo C and Donoso P. 2011. “Getting to the heart of mechanotransduction”. Science 333:1388-90. ISSN: 0036-8075. IF: 33.61

Donoso P, Sánchez G, Bull R, Hidalgo C. 2011. “Modulation of cardiac Ryanodine receptor activity by ROS and RNS”. Front Biosc. 16:553-567. ISSN: 1093-9946. IF: 4.249

Salas MA, Valverde CA, Sánchez G, Said M, Rodriguez JF, Portiansky EL, Kaetzel MA, Dedman JR, Donoso P ,   Kranias EG. and Mattiazzi A. 2010. “The Signaling Pathway of CAMKII-Mediated Apoptosis and Necrosis in the Ischemia/Reperfusion Injury”. J Mol Cell Cardiol. 48(6):1298-306. ISSN: 0022-2828. IF: 4.655

Pedrozo Z, Sánchez G, Torrealba N, Valenzuela R, Fernández C, Hidalgo C, Lavandero S and Donoso P. 2010. “Calpains and proteasomes mediate degradation of ryanodine receptors in a model of cardiac ischemic reperfusion”. Biochim Biophys Acta. 1802(3):356-62. ISSN: 0304-4165. IF: 4.381

Bull R, Finkelstein J P, Gálvez J, Sánchez G, Donoso P, Behrens MI, Hidalgo C. 2008. “Ischemia Enhances Activation by Ca2+ and Redox Modification of Ryanodine Receptor Channels from Rat Brain Cortex”. J. Neuroscience 28: 9463-72. ISSN: 1529-2401. IF: 6.344

Hidalgo C, Donoso P. 2008. “Cross Talk between Calcium and Redox Signaling: from Molecular. Mechanisms to Health Implications”. Antioxid Redox Signal. 10(7):1275-312. ISSN: 1523-0864. IF: 7.407