Doctor, en quimica, 2004, Universidad de la República Oriental del Uruguay, Uruguay
Líneas de Investigación
1.- Inmunovigilancia y evasion inmune. Estudio de ligandos de nkg2d en modelo tumoral y tolerancia fetal.
2.- Inmunobiotecnologia, generacion de anticuerpos recombinantes con fines terapeuticos.
3.- Desarrollo de metodología inmunológica
Publicaciones Recientes
1.-García-González P, Morales R, Hoyos L, Maggi J, Campos J, Pesce B, Gárate D, Larrondo M, González R, Soto L, Ramos V, Tobar P, Molina MC, Pino-Lagos K, Catalán D, Aguillón JC. 2013. “A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines”. J Transl Med. 2013;11:128. ISSN: 1479-5876 IF: 3.93.
2.- Pesce B, Soto L, Sabugo F, Wurmann P, Cuchacovich M, López MN, Sotelo PH, Molina MC, Aguillón JC, Catalán D. 2013. “Effect of interleukin-6 receptor blockade on the balance between regulatory T cells and T helper type 17 cells in rheumatoid arthritis patients”. Clin Exp Immunol. 2013;171(3):237-42. ISSN: 1365-2249. IF: 3.037
3.- Gárate D, Rojas-Colonelli N, Peña C, Salazar L, Abello P, Pesce B, Aravena O, García-González P, Ribeiro CH, Molina MC, Catalán D, Aguillón JC. 2013. “Blocking of p38 and transforming growth factor β receptor pathways impairs the ability of tolerogenic dendritic cells to suppress murine arthritis”. Arthritis Rheum ;65(1):120-9. ISSN: 2326-5205 IF: 7.764.
4.- Sotelo P, Collazo N, Zuñiga R, Gutiérrez-González M, Catalán D, Ribeiro CH, Aguillón JC, Molina MC. 2012. “An efficient method for variable region assembly in the construction of scFv phage display libraries using independent strand amplification”. MAbs. 2012 ;4(4):542-50. ISSN: 1942-0862. IF: 4.814
5.- Aravena O, Pesce B, Soto L, Orrego N, Sabugo F, Wurmann P, Molina MC, Alfaro J, Cuchacovich M, Aguillón JC, Catalán D. 2011. “Anti-TNF therapy in patients with rheumatoid arthritis decreases Th1 and Th17 cell populations and expands IFN-γ-producing NK cell and regulatory T cell subsets. Immunobiology. 2011; 216(12): 1256-1263. ISSN: 0171-2985. IF: 3.044
6.- Serrano AE, Menares-Castillo E, Garrido-Tapia M, Ribeiro CH, Hernández CJ, Mendoza-Naranjo A, Gatica-Andrades M, Valenzuela-Diaz R, Zúñiga R, López MN, Salazar-Onfray F, Aguillón JC, Molina MC. (2011). “Interleukin 10 decreases MICA expression on melanoma cell surface”. Immunol Cell Biol. 89(3):447-57. ISSN: 0818-9641. IF: 4.147.
7.- María C. Molina*, Ramirez G*, Valck C*, Ribeiro C, López N, Sánchez G, Ferreira V, Billetta R, Aguilar L, Maldonado I, Cattán P, Schwaeble W and Ferreira A (2011). “Trypanosoma cruzi calreticulin: a novel virulence factor that binds complement C1 on the parasite surface an promotes infectivity. Immunobiology 216(1-2):265-73. * contribuyeron igualmente. ISSN: 0171-2985. IF: 3.044
8.-Ribeiro CH, López NC, Ramírez GA, Valck CE, Molina MC, Aguilar L, Rodríguez M, Maldonado I, Martínez R, González C, Troncoso R, Lavandero S, Gingras AR, Schwaeble W, Ferreira A. (2009) “Trypanosoma cruzi calreticulin: A possible role in Chagas’ disease autoimmunity”. Mol Immunol 46(6):1092-9. ISSN: 0161-5890. IF: 2.973
9.-M. Mejías, M. C. Molina, A.Ferreira (2008) “Assessment of the IgG index in dogs by indirect immunoenzimatic assays as diagnostic tool for inflammatory diseases of central nervous”. Res Vet Sci. 84:(3)335-340. ISSN: 0034-5288. IF: 1.409
10.-Salazar L, Aravena O, Abello P, Escobar A, Contreras-Levicoy J,Rojas-Colonelli N, Catalán D, Aguirre A, Zúñiga R, Pesce B, González C, Cepeda R, Cuchacovich M, Molina MC, Salazar-Onfray F, Delgado M, Toes RE, Aguillón JC (2008) “Modulation of established murine collagen-induced arthritis by a single inoculation of short-term lipopolysaccharide-stimulated dendritic cells” Ann Rheum Dis. Sep;67(9):1235-41. ISSN: 0003-496. IF: 10.377