Magister en Ciencias Biológicas, mención Biología Celular, 1985, Universidad de Chile, Chile


Mecanismos Moleculares y Celulares involucrados en la etiopatogenesis de enfermedades autoinmunes.


1. Barrera MJ, Aguilera S, Veerman ECI, Quest AFG, Díaz-Jiménez D, Urzúa U, Cortés J, González S, Castro I, Molina C, Bahamondes V, Leyton L, Hermoso MA, and González MJ. 2015.  “Salivary mucins induce a TLR4-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjögren’s syndrome?” Rheumatology, doi:10.1093/rheumatology/kev026, 2015). ISSN: 1462-0332  IF: 4.212

2.  H.H. Sung, I. Castro, S. González, S. Aguilera, N.I. Smorodinsky, A.F.G. Quest, V. Bahamondes, C. Alliende, J. Cortés, C. Molina, U. Urzúa, M.J. Barrera, M. Hermoso, L. Herrera, C. Leyton and M.J. González. 2015 “MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjögren’s syndrome”. Oral Diseases, doi:10.1111/odi.12339, 2015..  ISSN: 1601-0825. IF: 2.427.

3. González S, Sung HH, Sepúlveda D, González MJ and Molina C.  2014. “Oral manifestations and their treatment in Sjögren’s syndrome. Oral Diseases, Mar;20(2):153-61. 2014 ISSN: 1601-0825. IF: 2.427.

4. De la Fuente M, Franchi L, Araya D, Díaz-Jiménez D, Olivares M, Álvarez-Lobos M, Golenbock D, González MJ, López-Kostner F, Quera R, Núñez G, Vidal R, Hermoso MA. 2014 “Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome. Int J Med Microbiol. 2014 May;304(3-4):384-92. ISSN: 1438-4221. IF: 3.614

5. Oyarzún G M, Pinto C ME, Raineri B GG, Amigo H, Cifuentes O L, González MJ, Horwitz N, Marshall F C, Orellana V G. 2014. “Experience of a research Ethics Committee and the challenges of the new Chilean legislation on research in human beings”. Rev Med Chil. 2014 Jul;142(7):889-95. doi: 10.4067/S0034-98872014000700009. ISSN:0034-9887. IF: 0.304

6. Castro I, Sepúlveda D, Cortés J, Quest AFG, Barrera MJ, Bahamondes V, Aguilera S, Urzúa U, Alliende C, Molina C, González S, Hermoso MA, Leyton C and González MJ. 2013. “Oral dryness in Sjögren’s syndrome patients. Not just a question of water”. Autoimmun Rev. 2013 Mar; 12(5):567-74. ISSN: 1568-9972 . IF: 7,975

7. Barrera MJ, Bahamondes V, Sepúlveda D, Quest AFG, Castro I, Cortés J, Aguilera S, Urzúa U, Molina C, Pérez P, Ewert P, Alliende C, Hermoso MA, González S, Leyton C and González MJ. 2013. “Sjögren’s Syndrome: Paradigm versus Paradox in Autoimmunity: A Comprehensive Review of Epithelial Cell Architecture and Pathogenic Mechanisms”. J Autoimmun. 2013 May;42:7-18.  ISSN:  0896-8411. IF: 8,145


8.  Marina Garcia, María-Julieta González, Rodrigo Quera and Marcela A Hermoso.  2013 “Innate immunity modulation by the Il-33/st2 system in intestinal mucosal”. Biomed Res Int. 2013;2013:142492. .ISSN: 1110-7243. IF: 0.409


9. María-José Barrera, Marianela Sánchez, Sergio Aguilera, Cecilia Alliende, Verónica Bahamondes, Claudio Molina, Andrew F.G. Quest, Ulises Urzúa, Isabel Castro, Sergio González, Hsiao Hsin Sung, Amelina Albornoz, Marcela Hermoso, Cecilia Leyton and María-Julieta González.  2012. “Aberrant Localization of Fusion Receptors Involved in Regulated Exocytosis In Salivary Glands Of Sjögren’s Syndrome Patients Is Linked To Ectopic Mucin Secretion”. Journal of Autoimmunity 39 (2012) 83-92.  ISSN:  0896-8411. IF: 8,145


10. Isabel Castro, Sergio Aguilera, Inka Brockhausen, Cecilia Alliende, Andrew F.G. Quest, Claudio Molina, Ulises Urzúa, Ulla Mandel, Verónica Bahamondes, María-José Barrera, Marianela Sánchez, Sergio González, Marcela Hermoso, Cecilia Leyton and María-Julieta González. 2012. “Dramatic decreased of salivary sulfotransferases activity correlated with inflammation and autoimmunity parameters in Sjögren’s syndrome patients”. Rheumatology (Oxford). 2012 Mar;51(3):482-90. Epub 2011 Nov 17  ISSN: 1462-0332  IF: 4.212