M.Sc. (2001) Universidad de Chile Ph.D. (2005)
Universidad de Chile
mhenriqu@med.uchile.cl
LÍNEAS DE INVESTIGACIÓN
Nuestra linea de investigación en el Laboratorio de Dinámicas Bronovasculares y Daño Pulmonar está orientada a dilucidar el Rol de los Receptores Purinérgicos en el Control de tono vascular pulmonar, particularmente estamos interesados en explorar nuevas vías fisiopatológicas en que aquellos receptores podrían estar involucrados. Recientemente hemos obtenido financiamiento (Fondecyt regular) para realizar estudios del tono vascular pulmonar en Hipertensión Pulmonar y la participación de receptores purinérgicos en su desarrollo.
Publicaciones Recientes
Ponce DP, Salech F, SanMartin CD, Silva M, Xiong C, Roe CM, Henriquez M, Quest AF, Behrens MI.2014. “Increased susceptibility to oxidative death of lymphocytes from Alzheimer patients correlates with dementia severity”. CURR ALZHEIMER RES. ISSN: 1567-2050. IF:3.889
Aguirre A, Shoji KF, Sáez JC, Henríquez M, Quest AF.2013.“FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between Fas and the purinergic receptor P2X(7)”. JOURNAL OF CELLULAR PHYSIOLOGY. ISSN: 1097-4652. IF: 3.839
Behrens, MI ,Silva M, Schmied A, Salech F, Manzur H, Rebolledo R, Bull R, Torres V, Henriquez M, Quest AF. 2011. “Age-Dependent Increases in Apoptosis/Necrosis Ratios in Human Lymphocytes Exposed to Oxidative Stress”. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. ISSN: 1079-5006. IF: 5.416
Henríquez M, Herrera-Molina R, Valdivia A, Alvarez A, Kong M, Muñoz N, Eisner V, Jaimovich E, Schneider P, Quest AF, Leyton L..2011. “ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation”. JOURNAL OF CELL SCIENCE. ISSN: 1477-9137. IF: 5.4
Jimenez, V ,Henriquez, M , Galanti, N. 2011.”Electrophysiological Characterization of Potassium Conductive Pathways in Trypanosomacruzi”. JOURNAL OF CELLULAR BIOCHEMISTRY. ISSN: 1097-4644. IF: 3-263
Mauricio Henriquez, Ricardo Armisen, Andres Stutzin and Andrew F.G. Quest – 2008. “Cell death by necrosis, a regulated way to go”. CURRENT MOLECULAR MEDICINE. ISSN: 1566-5240. IF: 3.621
Villena J, Henriquez M, Torres V, Moraga F, Díaz-Elizondo J, Arredondo C, Chiong M, Olea-Azar C, Stutzin A, Lavandero S,Quest AF. 2008. “Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells”. FREE RADICAL BIOLOGY AND MEDICINE. ISSN: 0891-5849. IF: 5.736
Bernucci L, Henríquez M, Díaz P, Riquelme G. 2007. “Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane”. PLACENTA. ISSN: 0143-4004. IF: 2.710
Llanos P, Henriquez M, Minic J, Elmorjani K, Marion D, Riquelme G, Molgó J, Benoit E. 2006.“Puroindoline-a and alpha 1-purothionin form ion channels in giant liposomes but exert different toxic actions on murine cells”. FEBS JOURNAL. ISSN: 1742-4658. IF: 4.001
Henriquez, M.2006. “VDAC-1 as the molecular correlate of the maxi chloride channel from human placental syncytiotrophoblast”. PLACENTA. ISSN: 0143-4004. IF: 2.710