Dentist (DDS: Doctor un Dental Surgery), Universidad de Chile, Chile

PhD in Dentistry Sciences, Universidad Complutense de Madrid, 2010, Spain

Research Lines

Inflammatory oral diseases.

Osteoimmunology of the oral and maxillofacial diseases.


Alvarez C, Rojas C, Rojas L, Cafferata EA, Monasterio G, Vernal R, 2018, Regulatory T lymphocytes in periodontitis. A translational view,Mediators Inflamm,accepted, ISSN: 0962-9351. Impact Factor:3.232

Monasterio G, Castillo F, Ibarra JP, Guevara J, Rojas L, Alvarez C, Fernández B, Agüero A, Betancur D, Vernal R, 2018, Alveolar bone resorption and Th1/Th17-associated immune response triggered during Aggregatibacter actinomycetemcomitans-induced experimental periodontitis are serotype-dependent, J Periodontol,accepted, ISSN: 0022-3492. Impact Factor:3.030

Bersezio C, Vildósola P, Sáez M, Sánchez F, Vernal R, Oliveira Jr OB, Jorquera G, Basualdo J, Loguercio A, Fernández E, 2018, Does the use of a “walking bleaching” technique increase bone resorption markers?, Oper Dent, 43(1):1-10,ISSN 0361-7734. Impact Factor: 2.893

Hernández-Caldera A, Vernal R, Paredes R, Veloso-Matta P. Astorga J, Hernández M, 2018, Human periodontal ligament fibroblasts synthesize C-reactive protein and Th-related cytokines in response to interleukin (IL)-6 trans-signalling,IntEndodJ, 51(5):10.1111/iej. 12872, ISSN 1365-2591. Impact Factor: 3.015

Pujol M, Castillo F, Alvarez C, Rojas C, Borie C, Ferreira A, Vernal R,2017,Variability in the response of canine and human dendritic cells stimulated with Brucella canis,Vet Res, 48(1):72,ISSN 0928-4249. Impact Factor: 2.798

Díaz-Zúñiga J, Melgar-Rodríguez S, Rojas L, Alvarez C, Monasterio G, Carvajal P, Vernal R, 2017, Increasedlevelsofthe Th22-associated cytokine (IL-22) andtranscription fator (AhR) in periodontitis patients are associatedwith osteoclast resorptive activityandseverityofthedisease, J Periodont Res,52(5):893-902,ISSN: 1600-0765. Impact Factor: 2.215

Díaz-Zúñiga J, Melgar-Rodríguez S, Monasterio G, Pujol M, Rojas L, Alvarez C, Carvajal P, Vernal R, 2017,Differentialhuman Th22-lymphocyte response triggeredbyAggregatibacter actinomycetemcomitans,Arch Oral Biol,78:26-33, ISSN 0003-9969. Impact Factor: 1.880

Hernández-Ríos P, Pussinen PJ, Vernal R, Hernández M, 2017, Oxidative stress in the local and systemic events of apical periodontitis, FrontPhysiol, 8:869,ISSN 1664-042X. Impact Factor: 4.134

Bersezio C, Martin J, Peña F, Rubio M, Estay J, Vernal R, Junior OO, Fernández E, 2017, Effectiveness and impact of the walking bleach technique on esthetic self-perception and psychosocial factors: A randomized double-blind clinical trial,Oper Dent, 42(6):596-605,ISSN 0361-7734. Impact Factor: 2.893

Salinas-Muñoz M, Garrido-Flores M, Baeza M, Huamán-Chipana P, García-Sesnich J. Bologna R, Vernal R, Hernández M, 2017, Bone resorptive activity in symptomatic and asymptomatic apical lesions of endodontic origin,Clin Oral Invest,21(8):2613-8,ISSN 1432-6981. Impact Factor: 2.308

Quiroz V, Reinero D, Hernández-Ríos O, Contreras J, Vernal R, Carvajal P, 2017,Developmentof a self-reportquestionnairedesignedpopulation-basedsurveillanceofgingivitis in adolescentes: Assessmentof contente validityandreliability, J Appl Oral Sci,25(4):404-11, ISSN: 1664-302X.ImpactFactor: 0.803

García K, Escobar G, Mendoza P, Bertran C, Perez C, Arancibia S, Vernal R, Rodas PI, Acuña-Castillo C, Escobar A,2016, ATP induces IL-1β secretion in Neisseriagonorrhoeae-infectedhumanmacrophagesby a mechanismnotrelatedtothe NLRP3/ASC/Caspase-1 axis,MediatorsInflamm,2016:1258504, ISSN: 0962-9351.ImpactFactor: 3.232

Soto C, Bugueño I, Hoare A, Gonzalez S, Venegas D, Salinas D, Melgar-Rodríguez S, Vernal R,Gamonal J, Quest AF, Pérez-Donoso JM,Bravo D, 2016, The Porphyromonas gingivalis O antigenisrequired for inhibitionofapoptosis in gingivalepithelialcellsfollowingbacterialinfection, J Periodont Res,51(4):518-28,ISSN: 1365-2958. ImpactFactor: 2.215

Melgar-Rodríguez S, Díaz-Zúñiga J, Alvarez C, Rojas L, Monasterio G, Carvajal P, Escobar A, Sanz M,Vernal R,2016, Serotype b ofAggregatibacter actinomycetemcomitansincreases osteoclast andmemory T-lymphocyteactivation,Mol Oral Microbiol,32(2):162-74,ISSN: 1932-6203. ImpactFactor: 2.842

Alvarez C, Benítez A, Rojas L, Pujol M, Carvajal P, Díaz-Zúñiga J,Vernal R,2015,DifferentialexpressionofCCchemokines (CCLs) andreceptors (CCRs) byhuman T lymphocytes in response to diferente Aggregatibacter actinomycetemcomitansserotypes, J Appl Oral Sci, 23(5):536-46, ISSN: 1664-302X.ImpactFactor: 0.803

Ortiz MC, Lefimil C, Rodas PI, Vernal R, Lopez M, Acuña-Castillo C, Imarai M, Escobar A,2015,Neisseriagonorrhoeaemodulatesimmunitybypolarizinghumanmacrophagesto a M2 profile,PLoS ONE,10(6):e0130713, ISSN: 1932-6203.ImpactFactor: 3.534

Silva N, Abusleme L, Bravo D, Dutzan N, Garcia-Sesnich J, Vernal R, Hernández M, Gamonal J,2015, Host response mechanisms in periodontal diseases, J Appl Oral Sci,23(3):329-55, ISSN: 1664-302X.ImpactFactor: 0.803

Retamal P, Fresno M, Dougnac C, Gutierrez S, Gornall V, Vidal R, Vernal R, Pujol M, Barreto M, González-Acuña D, Avalos P,2015,GeneticandphenotypicevidenceoftheSalmonellaentericserotypeEnteriditishuman-animal interfase in Chile, Front Microbiol,6(5):464, ISSN: 1600-0765. ImpactFactor: 3.941

Díaz-Zúñiga J, Melgar-Rodríguez S, Alvarez C, Monasterio G, Benítez A, Ciuchi P, Díaz Claudia, Mardones J, Escobar A, Sanz M, Vernal R. 2015, T-lymphocytephenotypeandfunctiontriggeredbyAggregatibacter actinomycetemcomitans isserotype-dependent, J Periodont Res,50(6):824-35, ISSN: 1600-0765. ImpactFactor: 2.215

Osorio C, Cavalla F, Paula-Lima A, Díaz-Araya G, Vernal R, Ahumada P, Gamonal J, Hernández M,2015, H2O2activatedmatrix metalloproteinases through nuclear factorkappa B pathwayand Ca2+signals in human periodontal fibroblastos, J Periodont Res, 50(6):798-806, ISSN: 1600-0765. ImpactFactor: 2.215

Garrido M, Dezerega A, Bordagaray MJ, Hernández A, Reyes M, Vernal R, Melgar-Rodríguez S, Ciuchi P, Paredes R, García-Sesnich J, Ahumada-Montalva P,Hernández M,2015, C-reactiveproteinexpressionisup-regulated in apical lesionsofendodonticorigin in associationwith interleukin-6, J Endod,41(4):464-9, ISSN: 0099-2399.ImpactFactor: 2.788

Díaz-Zúñiga J, Monasterio G, Alvarez C, Melgar-Rodríguez S, Benítez A, Ciuchi P, García M, Arias J, Sanz M,Vernal R,2015,Variability of the dendritic cell response triggered by the different serotypes of Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis is toll-like receptor 2 (TLR2) or TLR4-dependent,J Periodontol,86(1):108-19,ISSN: 0022-3492. Impact Factor:3.030

Vernal R, Díaz-Zúñiga J, Melgar-Rodríguez S, Pujol M, Diaz-Guerra E, Silva A, Sanz M,Garcia-Sanz JÁ,2014, Activationof RANKL-induced osteoclasts andmemory T lymphocytesbyPorphyromonas gingivalisisserotypedependant,J ClinPeriodontol,41(5):451-9, ISSN: 0303-6979. ImpactFactor:3.610

Díaz-Zúñiga J, Yáñez JP, Alvarez C, Melgar-Rodríguez S, Hernández M, Sanz M, Vernal R,2014, Serotype-dependent response ofhuman dendritic cellsstimulatedwithAggregatibacter actinomycetemcomitans,J ClinPeriodontol,41(3):242-51, ISSN: 0303-6979. ImpactFactor:3.610

Vernal R, Diaz-Guerra E, Silva A, Sanz M,Garcia-Sanz JÁ,2014, Distincthuman T-lymphocyte responses triggeredbyPorphyromonas gingivalis capsular serotypes, J ClinPeriodontol,41(1):19-30,ISSN: 0303-6979. ImpactFactor:3.610

Cavalla F, Reyes M, Vernal R, Alvarez C, Paredes R, García-Sesnich J, Infante M, Fariña V, Barrón I,Hernández M,2013, High levels of CXC ligand 12/stromal cell-derived factor 1 in apical lesions of endodontic origin associated with mast cell infiltration,J Endod, 39(10):1234-9,ISSN: 0099-2399.Impact Factor: 2.788

Barbieri G, Solano P, Alarcón JA, Vernal R, Ríos-Lugo J, Sanz M,Martín C, 2013,Biochemical markers of bone metabolism in gingival crevicular fluid during early orthodontic tooth movement,AngleOrthod, 83(1):63-9, ISSN: 0003-3219.ImpactFactor:1.277