Dentist (DDS: Doctor un Dental Surgery), Universidad de Chile, Chile
PhD in Dentistry Sciences, Universidad Complutense de Madrid, 2010, Spain
Research Lines
Inflammatory oral diseases.
Osteoimmunology of the oral and maxillofacial diseases.
Papers
Alvarez C, Rojas C, Rojas L, Cafferata EA, Monasterio G, Vernal R, 2018, Regulatory T lymphocytes in periodontitis. A translational view,Mediators Inflamm,accepted, ISSN: 0962-9351. Impact Factor:3.232
Monasterio G, Castillo F, Ibarra JP, Guevara J, Rojas L, Alvarez C, Fernández B, Agüero A, Betancur D, Vernal R, 2018, Alveolar bone resorption and Th1/Th17-associated immune response triggered during Aggregatibacter actinomycetemcomitans-induced experimental periodontitis are serotype-dependent, J Periodontol,accepted, ISSN: 0022-3492. Impact Factor:3.030
Bersezio C, Vildósola P, Sáez M, Sánchez F, Vernal R, Oliveira Jr OB, Jorquera G, Basualdo J, Loguercio A, Fernández E, 2018, Does the use of a “walking bleaching” technique increase bone resorption markers?, Oper Dent, 43(1):1-10,ISSN 0361-7734. Impact Factor: 2.893
Hernández-Caldera A, Vernal R, Paredes R, Veloso-Matta P. Astorga J, Hernández M, 2018, Human periodontal ligament fibroblasts synthesize C-reactive protein and Th-related cytokines in response to interleukin (IL)-6 trans-signalling,IntEndodJ, 51(5):10.1111/iej. 12872, ISSN 1365-2591. Impact Factor: 3.015
Pujol M, Castillo F, Alvarez C, Rojas C, Borie C, Ferreira A, Vernal R,2017,Variability in the response of canine and human dendritic cells stimulated with Brucella canis,Vet Res, 48(1):72,ISSN 0928-4249. Impact Factor: 2.798
Díaz-Zúñiga J, Melgar-Rodríguez S, Rojas L, Alvarez C, Monasterio G, Carvajal P, Vernal R, 2017, Increasedlevelsofthe Th22-associated cytokine (IL-22) andtranscription fator (AhR) in periodontitis patients are associatedwith osteoclast resorptive activityandseverityofthedisease, J Periodont Res,52(5):893-902,ISSN: 1600-0765. Impact Factor: 2.215
Díaz-Zúñiga J, Melgar-Rodríguez S, Monasterio G, Pujol M, Rojas L, Alvarez C, Carvajal P, Vernal R, 2017,Differentialhuman Th22-lymphocyte response triggeredbyAggregatibacter actinomycetemcomitans,Arch Oral Biol,78:26-33, ISSN 0003-9969. Impact Factor: 1.880
Hernández-Ríos P, Pussinen PJ, Vernal R, Hernández M, 2017, Oxidative stress in the local and systemic events of apical periodontitis, FrontPhysiol, 8:869,ISSN 1664-042X. Impact Factor: 4.134
Bersezio C, Martin J, Peña F, Rubio M, Estay J, Vernal R, Junior OO, Fernández E, 2017, Effectiveness and impact of the walking bleach technique on esthetic self-perception and psychosocial factors: A randomized double-blind clinical trial,Oper Dent, 42(6):596-605,ISSN 0361-7734. Impact Factor: 2.893
Salinas-Muñoz M, Garrido-Flores M, Baeza M, Huamán-Chipana P, García-Sesnich J. Bologna R, Vernal R, Hernández M, 2017, Bone resorptive activity in symptomatic and asymptomatic apical lesions of endodontic origin,Clin Oral Invest,21(8):2613-8,ISSN 1432-6981. Impact Factor: 2.308
Quiroz V, Reinero D, Hernández-Ríos O, Contreras J, Vernal R, Carvajal P, 2017,Developmentof a self-reportquestionnairedesignedpopulation-basedsurveillanceofgingivitis in adolescentes: Assessmentof contente validityandreliability, J Appl Oral Sci,25(4):404-11, ISSN: 1664-302X.ImpactFactor: 0.803
García K, Escobar G, Mendoza P, Bertran C, Perez C, Arancibia S, Vernal R, Rodas PI, Acuña-Castillo C, Escobar A,2016, ATP induces IL-1β secretion in Neisseriagonorrhoeae-infectedhumanmacrophagesby a mechanismnotrelatedtothe NLRP3/ASC/Caspase-1 axis,MediatorsInflamm,2016:1258504, ISSN: 0962-9351.ImpactFactor: 3.232
Soto C, Bugueño I, Hoare A, Gonzalez S, Venegas D, Salinas D, Melgar-Rodríguez S, Vernal R,Gamonal J, Quest AF, Pérez-Donoso JM,Bravo D, 2016, The Porphyromonas gingivalis O antigenisrequired for inhibitionofapoptosis in gingivalepithelialcellsfollowingbacterialinfection, J Periodont Res,51(4):518-28,ISSN: 1365-2958. ImpactFactor: 2.215
Melgar-Rodríguez S, Díaz-Zúñiga J, Alvarez C, Rojas L, Monasterio G, Carvajal P, Escobar A, Sanz M,Vernal R,2016, Serotype b ofAggregatibacter actinomycetemcomitansincreases osteoclast andmemory T-lymphocyteactivation,Mol Oral Microbiol,32(2):162-74,ISSN: 1932-6203. ImpactFactor: 2.842
Alvarez C, Benítez A, Rojas L, Pujol M, Carvajal P, Díaz-Zúñiga J,Vernal R,2015,DifferentialexpressionofCCchemokines (CCLs) andreceptors (CCRs) byhuman T lymphocytes in response to diferente Aggregatibacter actinomycetemcomitansserotypes, J Appl Oral Sci, 23(5):536-46, ISSN: 1664-302X.ImpactFactor: 0.803
Ortiz MC, Lefimil C, Rodas PI, Vernal R, Lopez M, Acuña-Castillo C, Imarai M, Escobar A,2015,Neisseriagonorrhoeaemodulatesimmunitybypolarizinghumanmacrophagesto a M2 profile,PLoS ONE,10(6):e0130713, ISSN: 1932-6203.ImpactFactor: 3.534
Silva N, Abusleme L, Bravo D, Dutzan N, Garcia-Sesnich J, Vernal R, Hernández M, Gamonal J,2015, Host response mechanisms in periodontal diseases, J Appl Oral Sci,23(3):329-55, ISSN: 1664-302X.ImpactFactor: 0.803
Retamal P, Fresno M, Dougnac C, Gutierrez S, Gornall V, Vidal R, Vernal R, Pujol M, Barreto M, González-Acuña D, Avalos P,2015,GeneticandphenotypicevidenceoftheSalmonellaentericserotypeEnteriditishuman-animal interfase in Chile, Front Microbiol,6(5):464, ISSN: 1600-0765. ImpactFactor: 3.941
Díaz-Zúñiga J, Melgar-Rodríguez S, Alvarez C, Monasterio G, Benítez A, Ciuchi P, Díaz Claudia, Mardones J, Escobar A, Sanz M, Vernal R. 2015, T-lymphocytephenotypeandfunctiontriggeredbyAggregatibacter actinomycetemcomitans isserotype-dependent, J Periodont Res,50(6):824-35, ISSN: 1600-0765. ImpactFactor: 2.215
Osorio C, Cavalla F, Paula-Lima A, Díaz-Araya G, Vernal R, Ahumada P, Gamonal J, Hernández M,2015, H2O2activatedmatrix metalloproteinases through nuclear factorkappa B pathwayand Ca2+signals in human periodontal fibroblastos, J Periodont Res, 50(6):798-806, ISSN: 1600-0765. ImpactFactor: 2.215
Garrido M, Dezerega A, Bordagaray MJ, Hernández A, Reyes M, Vernal R, Melgar-Rodríguez S, Ciuchi P, Paredes R, García-Sesnich J, Ahumada-Montalva P,Hernández M,2015, C-reactiveproteinexpressionisup-regulated in apical lesionsofendodonticorigin in associationwith interleukin-6, J Endod,41(4):464-9, ISSN: 0099-2399.ImpactFactor: 2.788
Díaz-Zúñiga J, Monasterio G, Alvarez C, Melgar-Rodríguez S, Benítez A, Ciuchi P, García M, Arias J, Sanz M,Vernal R,2015,Variability of the dendritic cell response triggered by the different serotypes of Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis is toll-like receptor 2 (TLR2) or TLR4-dependent,J Periodontol,86(1):108-19,ISSN: 0022-3492. Impact Factor:3.030
Vernal R, Díaz-Zúñiga J, Melgar-Rodríguez S, Pujol M, Diaz-Guerra E, Silva A, Sanz M,Garcia-Sanz JÁ,2014, Activationof RANKL-induced osteoclasts andmemory T lymphocytesbyPorphyromonas gingivalisisserotypedependant,J ClinPeriodontol,41(5):451-9, ISSN: 0303-6979. ImpactFactor:3.610
Díaz-Zúñiga J, Yáñez JP, Alvarez C, Melgar-Rodríguez S, Hernández M, Sanz M, Vernal R,2014, Serotype-dependent response ofhuman dendritic cellsstimulatedwithAggregatibacter actinomycetemcomitans,J ClinPeriodontol,41(3):242-51, ISSN: 0303-6979. ImpactFactor:3.610
Vernal R, Diaz-Guerra E, Silva A, Sanz M,Garcia-Sanz JÁ,2014, Distincthuman T-lymphocyte responses triggeredbyPorphyromonas gingivalis capsular serotypes, J ClinPeriodontol,41(1):19-30,ISSN: 0303-6979. ImpactFactor:3.610
Cavalla F, Reyes M, Vernal R, Alvarez C, Paredes R, García-Sesnich J, Infante M, Fariña V, Barrón I,Hernández M,2013, High levels of CXC ligand 12/stromal cell-derived factor 1 in apical lesions of endodontic origin associated with mast cell infiltration,J Endod, 39(10):1234-9,ISSN: 0099-2399.Impact Factor: 2.788
Barbieri G, Solano P, Alarcón JA, Vernal R, Ríos-Lugo J, Sanz M,Martín C, 2013,Biochemical markers of bone metabolism in gingival crevicular fluid during early orthodontic tooth movement,AngleOrthod, 83(1):63-9, ISSN: 0003-3219.ImpactFactor:1.277