Doctor en Ciencias, Mención Bioquímica y Biología Molecular, 1988, Universidad de Chile, Chile

Líneas de Investigación

Mecanismos de adaptación de microorganismos (Helicobacter pylori) al estrés ambiental.

Mecanismos de adherencia de microorganismos a los tejidos blancos

Publicaciones Recientes

Serrano, CA., Villagrán, A., Toledo, H., Crabtree, JE., Harris, PR. 2015. “Iron deficiency and IL1β polymorphisms in Helicobacter pylori-infected children”. Helicobacter. In press. ISSN: 1523-5378 IF: 4.106.


Cáceres, M., Ortiz L, Recabarren T, Romero A, Colombo A, Leiva-Salcedo E, Varela D, Rivas J, Silva I, Morales D, Campusano C, Almarza O, Simon F, Toledo H, Park K.S., Trimmer J.S., Cerda, O. 2015. “TRPM4 is a novel component of the adhesome required for focal adhesion disassembly, migration and contractility”. PloS One. ISSN: 1932-6203IF: 3.534


 Almarza O, Núñez D, Toledo H. 2015. “The DNA-binding protein HU has a regulatory role in the acid stress response mechanism in Helicobacter pylori”. Helicobacter. . ISSN: 1523-5378 IF: 4.106.


Valenzuela, M, Caceres, A, Almarza, O. Toledo-Araya, H 2014. “Characterization of the Arginine Decarboxylase Gene (ORF HP0422, speA) Involved in Acid Tolerance in Helicobacter pylor”. Helicobacter. ISSN: 1523-5378 IF: 4.106.


 Diaz-Gomez, R, Toledo-Araya, H, Lopez-Solis, R. 2014. “Combined effect of gallic acid and catechin against Escherichia coli”. LWT-FOOD SCIENCE AND TECHNOLOGY. ISSN: 0023-6438. IF: 2.468 (2013-2014)


Traipe-Castro, L, Salinas-Toro, D, Lopez, D., Toledo H. 2014. “Dynamics of tear fluid desiccation on a glass surface: a contribution to tear quality assessment” BIOL RES. ISSN: 0717-6287 IF: 1.480.


Toledo, H; Almarza, O. 2014. “The DNA binding protein HU from Helicobacter pylori participates in stress acid response”. Helicobacter. ISSN: 1523-5378 IF: 4.106.


Valenzuela, M, Bravo, D, Canales, J. Toledo, H; 2013. “Helicobacter pylori-Induced Loss of Survivin and Gastric Cell Viability Is Attributable to Secreted Bacterial Gamma-Glutamyl Transpeptidase Activity”. J Infect. Dis. ISSN: 1537-6613 IF: 5.778.


López Solís R, Traipe Castro L, Salinas Toro D, Srur M, Toledo Araya H. 2013. “Microdesiccates produced from normal human tears display four distinctive morphological components”. Biol Res. ISSN: 0717-6287. IF:1.480


Del Campo, M; Toledo, H; Lagos, N. 2013. “Okadaic Acid Toxin at Sublethal Dose Produced Cell Proliferation in Gastric and Colon Epithelial Cell Lines”. Marine drugs. ISSN: 1660-3397. IF:3.512 (2013-2014)