Doctor en Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, 2008, Chile

Participación de canales iónicos en procesos de migración celular

Regulación de canales TRP mediante modificaciones postraduccionales

Mecanismos de regulación del tráfico y localización de canales iónicos



Varela, D., Penna, A., Simon, F., Eguiguren, A. L., Leiva-Salcedo, E., Cerda, O., Sala, F., Stutzin, A. 2010. “P2X4 activation modulates volume-sensitive outwardly rectifying chloride channels in rat hepatoma cells”. J. Biol Chem. 285 (2010): 7566-7574. ISSN: 0021-9258. IF: 4.573


Cerda, O., Trimmer, J. S. 2010. “Analysis and functional implications of phosphorylation of neuronal voltage-gated potassium channels”. Neuroscience Letters 10 (2010): 486(2): 60-67. ISSN: 0304-3940. IF: 2.030


Simon, F., Leiva-Salcedo, E., Armisén, R., Riveros, A., Cerda, O., Eguiguren, A., Olivero, P., Stutzin, A. 2010. “Hydrogen peroxide removes TRPM4 current desensitization conferring increased vulnerability to necrotic cell death”. J. Biol. Chem. 285 (2010): 37150-37158. ISSN: 0021-9258. IF: 4.573


Cerda, O., Baek, J. H., Trimmer, J. S. 2011. “Mining recent brain proteomic databases for ion channel phosphosite nuggets”. J. Gen. Physiol. 137 (2011): 3–16. ISSN: 0022-1295. IF: 4.788


Vacher, H., Yang, J. Y., Cerda, O., Autillo-Touati, A., Dargent, Trimmer, J. S. 2011. “CDK-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting”. J. Cell Biol. 192 (2011): 813-824. (Highlighted in Faculty of 1000). ISSN: 0021-9525. IF: 9.834


Baek, J. H., Cerda, O., Trimmer, J. S. 2011. “Mass spectrometry-based phosphoproteomics reveals multisite phosphorylation on mammalian brain voltage-gated sodium and potassium channels”. Semin. Cell Dev Biol 22 (2011): 153-159 * Equal contribution. (Highlighted on the Cover). ISSN: 1084-9521. IF: 6.265



Mandikian, D., Cerda, O., Sack, J. T., Trimmer, J. S. A 2011. “SUMO-Phospho tag team for wrestling with potassium channel gating”. J. Gen. Physiol. 137 (2011): 435-439. ISSN: 0022-1295. IF: 4.788


Cerda, O., Trimmer, J. S. 2011. “Activity-Dependent Phosphorylation of Neuronal Kv2.1 Potassium Channels by CDK5”. J. Biol. Chem. 286 (2011): 28738–28748. (Highlighted on the Cover). ISSN: 0021-9258. IF: 4.573



Cerda O., Nuñez-Villena F., Soto S.E., Ugalde J.M., López-Solís R., Toledo H. 2011. tlpA gene expression is required for arginine and bicarbonate chemotaxis in Helicobacter pylori”. Biol Res 44 (2011): 277-282. ISSN: 0717-6287. IF: 1.480



Sarmiento, D., Montorfano, I., Cerda, O., Cáceres, M., Becerra, A., Cabello-Verrugio, C., Elorza, A.A., Riedel, C., Tapia, P., Velásquez, L.A., Varela, D., Simon, F. 2014. “Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel”. Microvasc Res. (2014) pii: S0026-2862 (14) 00032-6. doi: 10.1016/j.mvr.2014.02.001. [Epub ahead of print]. ISSN: 0026-2862. IF: 2126